TNF-Related Apoptosis-Inducing Ligand Receptors

Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.

Also Known As:

Receptors, TNF-Related Apoptosis-Inducing Ligand; APO2 Receptor; CD261 Antigen; CD262 Antigen; CD264 Antigen; DCR2 Receptor; DR4 Receptor; DR5 Receptor; Death Receptor-4; Death Receptor-5; Receptor, TRAIL-1; Receptor, TRAIL-2; Receptor, TRAIL-4; Receptors, Tumor Necrosis Factor, Member 10a; Receptors, Tumor Necrosis Factor, Member 10d; TNF-Related Apoptosis-Inducing Ligand Receptor 2; TRAIL Receptor 1; TRAIL Receptor 2; TRAIL Receptor 4; TRAIL Receptors; Tumor Necrosis Factor Receptor Superfamily, Member 10a; Tumor Necrosis Factor Receptor Superfamily, Member 10b; Antigen, CD261; Antigen, CD262; Antigen, CD264; Death Receptor 4; Death Receptor 5; Receptor 4, TRAIL; Receptor, APO2; Receptor, DCR2; Receptor, DR4; Receptor, DR5; Receptor, TRAIL 1; Receptor, TRAIL 2; Receptor, TRAIL 4; Receptor-4, Death; Receptors, TNF Related Apoptosis Inducing Ligand; TNF Related Apoptosis Inducing Ligand Receptor 2; TNF Related Apoptosis Inducing Ligand Receptors; TRAIL-1 Receptor; TRAIL-2 Receptor; TRAIL-4 Receptor; Decoy Receptor 2, Tumor Necrosis Factor; Receptors, TRAIL; Receptors, Tumor Necrosis Factor, Member 10; Receptors, Tumor Necrosis Factor, Member 10b; Tumor Necrosis Factor Receptor Superfamily, Member 10

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Death Domain Receptors: 2368
        TNF-Related Apoptosis-Inducing Ligand Receptors: 813
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Tumor Necrosis Factor Receptors: 3685
        TNF-Related Apoptosis-Inducing Ligand Receptors: 813

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Disease

Drug/Important Bio-Agent (IBA)